Every once in a while, for whatever reason, my Bamboo Pen stops responding. I happen to use Windows 7, and I’m not exactly sure why this happens. What I DO know is how to fix it.
Open up your “Bamboo Preference File Utility” ("C:\Program Files\Tablet\Pen\PrefUtil.exe")
Once that opens, under “All User Preferences”, click “Remove”.
This will reset all your settings, but your Bamboo Pen should start right back up!